Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. New York City

Best Gluten Free Restaurants in Little Italy, New York City

Price
Cuisine
Regions
Areas
Top Rated
Dining Options
Seating Options
Award-winning
Accessibility

78 restaurants available nearby

How are Featured results ranked

A photo of Senza Gluten restaurant
4.7
Exceptional(2680)
$$$$
• Italian • Greenwich Village
Booked 38 times today
Senza Gluten is the first 100% gluten-free Italian restaurant in Greenwich Village, NYC, offering a completely celiac-safe dining experience with zero risk of cross-contamination. Located near Washington Square Park, we are a top destination for gluten-free dining in New York City.We understand that dining out gluten-free can be challenging, and our mission is to provide a safe, welcoming space where guests can enjoy authentic Italian cuisine with confidence. Our menu features classic Italian favorites made entirely without gluten, including homemade pasta, pizza, lasagna, gnocchi, and tiramisu. With a warm, cozy atmosphere, Senza Gluten is perfect for date nights, group dinners, and special occasions. Whether you're searching for a celiac-friendly restaurant, gluten-free Italian food, or a safe place to enjoy pasta and pizza in NYC, Senza Gluten delivers a dining experience that is both comforting and exceptional.Please note: We accept cash and American Express only.
A photo of The Butcher's Daughter - Nolita restaurant
4.3
Awesome(141)
$$$$
• American • NoLita
Booked 16 times today
A plant-forward café, restaurant, and wine bar in the heart of Nolita, The Butcher’s Daughter sits between Soho and Elizabeth Street Garden and has become a downtown destination for seasonal dining and natural wine. Known for fresh, vegetable-driven vegetarian and vegan dishes, we serve breakfast, brunch, lunch, and dinner.Led by Executive Chef Samia Behaya, the menu features seasonal plates, house-baked breads and pastries, cold-pressed juices, organic coffee, craft cocktails, and a curated selection of natural wines. By day, the Corner Market offers juices, pastries, pantry goods, and grab-and-go essentials before transitioning at 4 PM into a natural wine bar with shareable bites, bringing an intimate evening energy to the neighborhood.A multi-time OpenTable Diner’s Choice Award winner, The Butcher’s Daughter Nolita also offers catering and private dining for gatherings and downtown celebrations.
A photo of Gelso and Grand restaurant
4.6
Exceptional(124)
$$$$
• Italian • Little Italy
Booked 9 times today
Conceived by a Mulberry street local that was motivated to push the boundaries of a historic block that is in search of its reinvention. Gelso & Grand is situated at the iconic corner of Mulberry & Grand Street. The inviting and informal seating plan of the indoor, outdoor and private dining room boasts the marriage of modern and classic New York dining. We take pride in everything we do. We make all pastas in house, we use a wood fired brick oven for our pizzas. We are an upscale-casual restaurant serving modern Italian fare.
A photo of Antique Garage Soho restaurant
4.7
Exceptional(1095)
$$$$
• Mediterranean • TriBeCa
Booked 13 times today
Antique Garage SoHo is converted from an old mechanic shop to a Mediterranean restaurant surrounded by antiques offers an eclectic, unique and romantic ambiance, charming and elegant in the tradition of old New York. We have a sister location in Tribeca.We serve lunch and dinner daily as well as brunch on weekends, accompanied by live jazz music.For parties of 12-20 more, Antique Garage offers a prix fixe menu.Antique Garage is delighted to welcome larger parties and private events. For more information, please visit our website. If you'd like to reach out to our team directly, you can email us at events@antiquegarage.com.
A photo of Il Cortile Restaurant restaurant
4.8
Exceptional(1741)
$$$$
• Italian • Little Italy
Booked 12 times today
IL Cortile has been family owned and run since 1975. A neighborhood staple in the heart of Little Italy, NYC for over 50 years the Esposito family continues the tradition of sparing nothing to provide only the highest quality ingredients in all Cortile dishes.We are a full Service Restaurant Establishment offering both A-La-Carte dining and a wide variety of pre-fix menus for group gatherings as well as off premise catering. We can accommodate gluten free and vegan diets. Everything is made to order.
A photo of Eataly NYC Soho - Il Ristorante restaurant
4.5
Awesome(371)
$$$$
• Pizzeria • SoHo
Booked 4 times today
Located within Eataly SoHo, Eataly Ristorante celebrates the essence of iconic Italian cuisine in a convivial, lively setting. Watch expert pizzaioli prepare traditional Neapolitan pies in golden wood-burning ovens, and savor a rotating selection of perfectly al dente pasta dishes rooted in Italy's most beloved regional recipes. Open for lunch, dinner, and weekend brunch, the restaurant pulses with the vibrant energy of an Italian marketplace, whether you're stopping in for a quick weekday lunch, settling in for aperitivo hour on the patio, or gathering for a leisurely weekend meal accompanied by live music. Ask your server about our rotating specials and tableside experiences that bring a little extra Italian flair to every visit.
A photo of Casa D’Angelo New York restaurant
4.8
Exceptional(563)
$$$$
• Italian • Little Italy
Booked 11 times today
Casa D’Angelo – Little ItalyStep into one of Mulberry Street’s oldest Italian restaurants and a longtime favorite among locals and visitors alike. Casa D’Angelo is renowned for its Fresh, Homemade Pasta.Specialties that include Cheese-Wheel Pasta, Osso Buco, Linguine alla Pescatore, Bistecca alla Fiorentina, and Authentic Brick Oven Pizzas.Over the years, our tables have welcomed countless notable guests, including President Ronald Reagan, Sophia Loren, Mario Merola, Diego Maradona, Kobe Bryant, and Magic Johnson. The restaurant’s walls tell the story of Little Italy’s rich cultural history, from the bustling streets of the early 20th century to today’s vibrant New York City. Experience true Italian hospitality in the heart of Little Italy.
A photo of The Crosby Bar restaurant
4.8
Exceptional(1097)
$$$$
• American • SoHo
Booked 44 times today
The Crosby Bar & Terrace is located on a quiet, cobblestoned street inside Soho’s Crosby Street Hotel. We offer modern American cuisine in a spacious room with high ceilings, long pewter bar, gray oak floors and tall warehouse-style windows which look out to the trees at the hotel’s entrance and the garden on Lafayette. It has an altogether leafy, breezy feel with lots of light throughout the day.
A photo of Palma restaurant
4.8
Exceptional(3748)
$$$$
• Italian • Greenwich Village
Booked 76 times today
Palma is nested on quaint Cornelia Street in the heart of Greenwich Village, with a hidden garden filled with fresh flowers in all seasons and a 200-year-old Carriage House for private dining in an elegant yet warm setting. White Stucco walls, beamed ceilings, a salvaged chestnut door & a beautiful garden with ivy-covered walls create an atmosphere where people relax and enjoy life with food and wine. Palma is an organic Italian restaurant, offering a taste of Italian clean food since April 2001. We stay true to generations of our family's cherished recipes and techniques. Our ingredients arrive fresh each day from Palma's garden and local markets. The menu highlights housemade pastas, fresh seafood and seasonal produce.
A photo of Locanda Verde Tribeca restaurant
4.6
Exceptional(2515)
$$$$
• Italian • TriBeCa
Booked 31 times today
Locanda Verde is a casual, bustling neighborhood Italian taverna located in Robert De Niro's TriBeCa hotel, The Greenwich. The airy, light-flooded space is open morning, noon and night serving award-winning Chef Andrew Carmellini's inspired urban Italian cooking with home-style desserts and an all-day bakery counter by Pastry Chef Deborah Racicot.

See what locals rave about

From verified diners like you
From verified diners like you
  • Laurie
    Minneapolis - St. Paul •6 reviews
    5.0
    Dined 5 days ago
    Attentive service. Great food. Pretty ambiance. The waiters even sang Happy Birthday to me at the spur of the moment. Highly recommend.
    More info
    Il Cortile Restaurant$$$$• Italian• Little Italy
    4.8
  • Nick
    1 review
    5.0
    Dined 6 days ago
    What a fantastic dining experience! We started with the Antipasto Italiano, which was the perfect way to begin our meal. The drinks were excellent and complemented everything beautifully. For the main course, we shared the Bistecca alla Fiorentina for two, and it was cooked to perfection. We also tried the special of the night, which was absolutely amazing. Thank you to the entire team for a wonderful evening. We’ll definitely be back soon!
    More info
    Casa D’Angelo New York$$$$• Italian• Little Italy
    4.8
  • Erin
    New York City •12 reviews
    5.0
    Dined 6 days ago
    Took clients and team for a business lunch. One of our clients had never been to New York, so this was the perfect ambiance of the cool, Soho vibe without being over the top. We split many mezzes, salads and kabobs. It was a perfect mix considering we had vegetarians in our group.
    More info
    Antique Garage Soho$$$$• Mediterranean• TriBeCa
    4.7
  • LisaGold
    Washington, D.C. Area •11 reviews
    5.0
    Dined on 1 June 2026
    Great service and the food is consistently delicious!
    More info
    Gelso and Grand$$$$• Italian• Little Italy
    4.6
  • Teresa
    Caribbean •1 review
    5.0
    Dined on 1 June 2026
    I can’t even begin to describe how wonderful the food, service and overall vibe was at Senza Gluten! Everything was meticulously curated in its simplicity - the cuisine didn’t need gimmicks it was just spectacular! We will certainly return along with some of our friends and family, who are already making plans! Thanks again, and Arda, you were an amazing representative of your brand. Grazie mille, Teresa y John
    More info
    Senza Gluten$$$$• Italian• Greenwich Village
    4.7
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Businesses
  • Restaurant Management Solutions
  • Restaurant Booking Software
  • Restaurant Marketing Software
  • Restaurant Event Software
  • OpenTable For Restaurants
  • OpenTable For Restaurant Groups
  • Restaurant Resources
  • OpenTable Pricing & Plans
Join us on
  • Privacy policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Accessibility Statement
  • Cookie Preferences
Copyright © 2026 OpenTable Australia Level 22, 357 Collins Street, Melbourne, Victoria
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo